News Analysis: Steroids and Back Pain: An Uneasy Match

RANDALL KINNAIRD’S legal clients had steroids injected into their backs last summer for a wide range of reasons. Of the 25, one got three shots in a two-month period when pain never totally disappeared. Another got one as a preventive measure because she was going on a trip to Europe and was worried that cobblestones would aggravate an old injury. Now the 25 — or their survivors — have...

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Black Friday: A survival guide

Shopping The plan | The numbers | The gear | The strategy | The apps | The start Black Friday, the most buzzed-about shopping day of the year, is starting even earlier this holiday season as retailers try to get a jump on the competition. The official kickoff to the Christmas shopping rush,...

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Veteran L.A. County sheriff's deputy charged with murder

After spending much of his life putting people behind bars, a veteran L.A. County sheriff's deputy stood in handcuffs Thursday,...

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Ruckus Wireless prices IPO at high end of range: market source

(Reuters) – WiFi products maker Ruckus Wireless Inc priced its initial public offering at $ 15 per share, the high end of its expected price range, a market source told Reuters.The company, which is backed by Google Inc‘s Motorola Mobility LLC and venture capital firm Sequoia Capital, raised $ 126 million by selling 8.4 million shares. Ruckus...

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4 Latin Grammys to Jesse & Joy, Juanes wins too

LAS VEGAS (AP) — Mexican brother-sister duo Jesse & Joy and their pop hit "Corre!" ran away with four awards at the 13th Annual Latin Grammys, but Colombian rockero Juanes danced away with the award for best album for "MTV Unplugged" Thursday night."What a great joy. Thank God, and all the fans," Juanes said as he dragged Dominican mereguero Juan Luis Guerra, who produced the album, to the stage...

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Change Rattles Leading Health-Funding Agency

Major changes erupted at one of the world’s leading health-funding agencies Thursday as it hired a new director, dismissed the inspector general who had clashed with a previous director and announced a new approach to making grants. Alex Wong/Getty ImagesDr. Mark Dybul, who led the President's Emergency Plan for AIDS Relief, in 2007. Dr. Mark Dybul, the...

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JPMorgan's California energy dealings draw more fire

State and federal energy regulators moved on two fronts against the giant investment bank JPMorgan Chase & Co. over its...

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L.A. County sheriff's deputy held in fatal off-duty shooting

A veteran Los Angeles County sheriff's deputy was arrested Wednesday for allegedly shooting and killing a man in Sylmar while...

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Erdrich wins National Book Award for fiction

NEW YORK (AP) — The National Book Awards on Wednesday honored both longtime writers and new authors, from Louise Erdrich for "The Round House" to Katherine Boo for her debut work, "Beyond the Beautiful Forevers."Erdrich, 58, has been a published and highly regarded author for nearly 30 years but had never won a National Book Award until being cited Wednesday for her story, the second of a planned...

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Alzheimer’s Tied to Mutation Harming Immune Response

Alzheimer’s researchers and drug companies have for years concentrated on one hallmark of Alzheimer’s disease: the production of toxic shards of a protein that accumulate in plaques on the brain. But now, in a surprising coincidence, two groups of researchers working from entirely different starting points have converged on a mutated gene involved in another aspect of Alzheimer’s disease:...

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